Therapeutic potential of hydrolysable tannin on weight management oxidative stress and reproductive health in polycystic rats

Phytonutrients get attention now days due to their wide application and tendency improve the productive reproductive performance in humans. Hydrolysable tannin (HT) is one of these bionutrients. The present study was aimed investigate therapeutic effect HT on induced polycystic ovarian syndrome (PCOS) rats. Forty-five adult female rats with 4 5 regular estrous cycle were selected. PCOS by a single intramuscular injection Estradiol Valerate mg/rat/kg. offered 0.5, 1, 1.5 2% HT/kg body weight through oral gavage for two months. results had shown reduction (p<0.05) average feed intake, gain, total oxidative stress nutrient digestibility Similar trend serum luteinizing hormone insulin observed; while follicular stimulating hormone, prolactin antioxidant capacity improved (p<0.05). histopathology showed no signs cystic follicles improvement observed healthy follicles. concluded that treatment 1.5% level best potential management, health